{"id":12288,"date":"2024-04-05T14:01:38","date_gmt":"2024-04-05T14:01:38","guid":{"rendered":"https:\/\/olmix.com\/?p=12288"},"modified":"2024-11-08T17:46:34","modified_gmt":"2024-11-08T16:46:34","slug":"centralization-mycotoxin-data-single-database-mycocentral","status":"publish","type":"post","link":"https:\/\/mycokingdom.net\/en\/centralization-mycotoxin-data-single-database-mycocentral\/","title":{"rendered":"Centralization of all mycotoxin data in a single database: MycoCentral"},"content":{"rendered":"[vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; constrain_group_4=&#8221;yes&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; 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gradient_type=&#8221;default&#8221;][vc_column_text el_class=&#8221;med&#8221;]<strong><span class=\"TextRun SCXW7229611 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW7229611 BCX0\">Extensive information is available about mycotoxins<\/span><\/span><span class=\"TextRun SCXW7229611 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW7229611 BCX0\">: their <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW7229611 BCX0\">physico<\/span><span class=\"NormalTextRun SCXW7229611 BCX0\">-chemical properties, toxicity, kinetics, producing fungi, etc. Meanwhile, <\/span><span class=\"NormalTextRun SCXW7229611 BCX0\">this information is scattered across the Web and in the literature.<\/span> <\/span><\/strong>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; top_padding=&#8221;2%&#8221; constrain_group_1=&#8221;yes&#8221; bottom_padding=&#8221;2%&#8221; text_align=&#8221;left&#8221; row_position=&#8221;default&#8221; row_position_tablet=&#8221;inherit&#8221; row_position_phone=&#8221;inherit&#8221; overflow=&#8221;visible&#8221; pointer_events=&#8221;all&#8221;][vc_column_inner column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; overflow=&#8221;visible&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221;][vc_column_text]<span data-contrast=\"auto\">The work of Habauzit <\/span><i><span data-contrast=\"auto\">et al.<\/span><\/i><span data-contrast=\"auto\"> consisted in creating a <\/span><b><span data-contrast=\"auto\">central database to gather, in a single location, existing data on mycotoxins<\/span><\/b><span data-contrast=\"auto\"> as well as predictive information.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">A list of <\/span><b><span data-contrast=\"auto\">904 mycotoxin compounds<\/span><\/b><span data-contrast=\"auto\"> was established and associated with <\/span><b><span data-contrast=\"auto\">1192 mycotoxin-producing fungi<\/span><\/b><span data-contrast=\"auto\">. Existing information on their <\/span><b><span data-contrast=\"auto\">biosynthesis and metabolic pathways<\/span><\/b><span data-contrast=\"auto\">, as well as <\/span><b><span data-contrast=\"auto\">physico-chemical properties<\/span><\/b><span data-contrast=\"auto\">, <\/span><b><span data-contrast=\"auto\">kinetics<\/span><\/b><span data-contrast=\"auto\"> (Absorption, Distribution, Metabolism and Excretion) and <\/span><b><span data-contrast=\"auto\">toxicity<\/span><\/b><span data-contrast=\"auto\"> were <\/span><b><span data-contrast=\"auto\">harmonized and added to MycoCentral<\/span><\/b><span data-contrast=\"auto\">. Direct links to other databases and source of the information are provided to ensure traceability.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">MycoCentral is a dynamic database which will be improved by adding new information and functionality with time, as well as refining the prediction values.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span>[\/vc_column_text][image_with_animation image_url=&#8221;12277&#8243; image_size=&#8221;full&#8221; animation_type=&#8221;entrance&#8221; animation=&#8221;None&#8221; animation_movement_type=&#8221;transform_y&#8221; hover_animation=&#8221;none&#8221; alignment=&#8221;&#8221; border_radius=&#8221;none&#8221; box_shadow=&#8221;none&#8221; image_loading=&#8221;default&#8221; max_width=&#8221;100%&#8221; max_width_mobile=&#8221;default&#8221;][vc_column_text]<em><span style=\"font-weight: 400;\">Figure 1: MycoCentral homepage <\/span><\/em>[\/vc_column_text][image_with_animation image_url=&#8221;12279&#8243; image_size=&#8221;full&#8221; animation_type=&#8221;entrance&#8221; animation=&#8221;None&#8221; animation_movement_type=&#8221;transform_y&#8221; hover_animation=&#8221;none&#8221; alignment=&#8221;&#8221; border_radius=&#8221;none&#8221; box_shadow=&#8221;none&#8221; image_loading=&#8221;default&#8221; max_width=&#8221;100%&#8221; max_width_mobile=&#8221;default&#8221;][vc_column_text]<em><span style=\"font-weight: 400;\"> Figure 2: Example of the biosynthesis and metabolic pathways of the aflatoxin family <\/span><\/em>[\/vc_column_text][divider line_type=&#8221;Full Width Line&#8221; line_thickness=&#8221;1&#8243; divider_color=&#8221;accent-color&#8221; custom_height=&#8221;20&#8243;][vc_column_text]<span class=\"TextRun SCXW164688720 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\" data-ccp-parastyle-defn=\"{&quot;ObjectId&quot;:&quot;e55966f6-f1e0-43e1-9b0f-f3a539ae0355|39&quot;,&quot;ClassId&quot;:1073872969,&quot;Properties&quot;:[469775450,&quot;Default&quot;,201340122,&quot;2&quot;,134233614,&quot;true&quot;,469778129,&quot;Default&quot;,335572020,&quot;1&quot;,201342448,&quot;1&quot;,469777841,&quot;Charis SIL&quot;,469777842,&quot;Charis SIL&quot;,469777843,&quot;Aptos&quot;,469777844,&quot;Charis SIL&quot;,469769226,&quot;Charis SIL,Aptos&quot;,335551500,&quot;0&quot;,268442635,&quot;24&quot;,335559740,&quot;240&quot;,201341983,&quot;0&quot;,335559739,&quot;0&quot;]}\">Reference: <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">Habauzit<\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\"> D., <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">Lem\u00e9e<\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\"> P., <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">Fessard<\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\"> V.<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">MycoCentral<\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">: An innovative database to compile information on mycotoxins and <\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">facilitate<\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\"> hazard prediction<\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">. <\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">Food Control (<\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">202<\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">4)<\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">, 15<\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">9<\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">, <\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">110273<\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">.<\/span><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-parastyle=\"Default\">\u00a0<\/span><\/span><span class=\"TextRun Underlined SCXW164688720 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW164688720 BCX0\" data-ccp-charstyle=\"Hyperlink\"> https:\/\/doi.org\/10.1016\/j.foodcont.2023.110273<\/span><\/span><span class=\"EOP SCXW164688720 BCX0\" data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row type=&#8221;in_container&#8221; 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