{"id":16795,"date":"2025-01-21T17:33:07","date_gmt":"2025-01-21T16:33:07","guid":{"rendered":"https:\/\/mycokingdom.net\/?p=16795"},"modified":"2025-01-23T16:26:15","modified_gmt":"2025-01-23T15:26:15","slug":"tackling-deoxynivalenol-in-dairy-farming","status":"publish","type":"post","link":"https:\/\/mycokingdom.net\/en\/tackling-deoxynivalenol-in-dairy-farming\/","title":{"rendered":"Tackling Deoxynivalenol in Dairy Farming"},"content":{"rendered":"\r\n
January 21, 2024<\/p>\r\n\r\n\r\n\r\n
Reading Time: 2 minutes<\/p>\r\n\r\n\r\n\r\n
In t<\/span>his <\/span>Myco\u2019News<\/span>, we spotlight <\/span>recent<\/span> findings on deoxynivalenol (DON) <\/span>posing significant threats to dairy cow health, rumen function, and milk production. Here are the three main insights from recent research<\/span> done <\/span><\/span>in vivo<\/span><\/span> in China<\/span>:<\/span><\/span>\u00a0<\/span><\/strong><\/p>\r\n
Disruption of<\/span> r<\/span>umen <\/span>f<\/span>unction and <\/span>m<\/span>icrobiota<\/span><\/span>\u00a0<\/span><\/span><\/h3>\r\n
DON contamination in feed significantly disrupts rumen fermentation. It reduces volatile fatty acids (VFAs) such as propionate and butyrate, which are essential for energy production in <\/span>ruminant<\/span>s. Moreover, DON alters the microbial ecosystem in the rumen, decreasing beneficial bacteria like <\/span><\/span>Lachnospiraceae<\/span><\/span> and <\/span><\/span>Butyrivibrio<\/span><\/span>. These <\/span>disturbances<\/span> reduce nutrient digestion efficiency and <\/span>ultimately affect<\/span> milk yield.<\/span><\/span>\u00a0<\/span><\/p>\r\n
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Figure <\/span><\/span>1<\/span><\/span><\/span>. Total volatile fatty acid (TVFA), acetate, propionate and butyrate production of cows expose to low (L<\/span>; 20.8%<\/span>) and high (H<\/span>; 27.8%<\/span>) levels of starch (s)<\/span>;<\/span> and<\/span> low (L; 0.34 ppm) and high (H; 3.09 ppm) of <\/span>DON (d).<\/span><\/span>\u00a0<\/span><\/em><\/p>\r\n
High level of starch in the TMRs exacerbate the negative effects of DON. These diets promote rumen acidosis, increasing microbial imbalance and reducing DON detoxification capacity. High-starch, DON-contaminated diets led to a sharp decline in milk yield and increased oxidative stress compared to low-starch TMRs.<\/span>\u00a0<\/span><\/p>\r\n
Health Implications and Prevention<\/span>\u00a0<\/h3>\r\n
Beyond production losses, DON elevates oxidative stress indicators (ROS) and inflammation markers (TNF-\u03b1, IL-1\u03b2 and IFN-\u03b3). The immune response of cows was also negatively affected by DON, increasing IgG and complement 4 (C4). <\/span>\u00a0<\/span><\/p>\r\n
Effective strategies to mitigate DON impact include optimizing feed composition, regularly <\/span>monitoring<\/span> DON<\/span> contamination levels<\/span> in feeds<\/span>, and <\/span>incorporat<\/span>e a<\/span> detoxifier<\/span>. Maintaining a balanced diet, especially one lower in starch, is essential for reducing the severity of DON effects on rumen health and overall cow well-being.<\/span><\/span>\u00a0<\/span><\/p>\r\n
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Reference: Dong J<\/span>., Zhao Z., Wang Z., Li S., Zhang Y., Sun Z., Qin G., Zhang<\/span> X., Zhao W. <\/span>Demelash<\/span> N<\/span>., Wang <\/span>T.<\/span> and Zhen Y. 2024. Impact of deoxynivalenol on rumen function, production, and health<\/span> of dairy cows: Insights from metabolomics and microbiota analysis<\/span>. Journal of <\/span>Hazardoud<\/span> Materials, <\/span><\/span>465<\/span>. <\/span><\/span>https:\/\/doi.org\/10.1016\/j.jhazmat.2023.133376<\/span><\/span>\u00a0<\/span><\/p>\r\n
<\/p>","protected":false},"excerpt":{"rendered":"
January 21, 2024 Reading Time: 2 minutes In this Myco\u2019News, we spotlight recent findings on deoxynivalenol (DON) posing significant threats to dairy cow health, rumen function, and milk production. Here…<\/p>\n","protected":false},"author":3,"featured_media":16805,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[38,54,56,57,53,1],"tags":[],"class_list":{"0":"post-16795","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-myco-news-3","8":"category-myco-news-en","9":"category-myco-news-en-2","10":"category-myco-news-en-3","11":"category-myconews-en","12":"category-non-classifiee"},"_links":{"self":[{"href":"https:\/\/mycokingdom.net\/en\/wp-json\/wp\/v2\/posts\/16795","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mycokingdom.net\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mycokingdom.net\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mycokingdom.net\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/mycokingdom.net\/en\/wp-json\/wp\/v2\/comments?post=16795"}],"version-history":[{"count":2,"href":"https:\/\/mycokingdom.net\/en\/wp-json\/wp\/v2\/posts\/16795\/revisions"}],"predecessor-version":[{"id":16803,"href":"https:\/\/mycokingdom.net\/en\/wp-json\/wp\/v2\/posts\/16795\/revisions\/16803"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mycokingdom.net\/en\/wp-json\/wp\/v2\/media\/16805"}],"wp:attachment":[{"href":"https:\/\/mycokingdom.net\/en\/wp-json\/wp\/v2\/media?parent=16795"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mycokingdom.net\/en\/wp-json\/wp\/v2\/categories?post=16795"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mycokingdom.net\/en\/wp-json\/wp\/v2\/tags?post=16795"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
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