{"id":12305,"date":"2024-04-05T14:01:51","date_gmt":"2024-04-05T14:01:51","guid":{"rendered":"https:\/\/olmix.com\/?p=12305"},"modified":"2025-01-14T16:32:15","modified_gmt":"2025-01-14T15:32:15","slug":"dau-an-sinh-hoc-ve-phoi-nhiem-voi-fumonisins-o-ga","status":"publish","type":"post","link":"https:\/\/mycokingdom.net\/vi\/dau-an-sinh-hoc-ve-phoi-nhiem-voi-fumonisins-o-ga\/","title":{"rendered":"D\u1ea5u \u1ea5n sinh h\u1ecdc v\u1ec1 ph\u01a1i nhi\u1ec5m v\u1edbi fumonisins \u1edf g\u00e0?"},"content":{"rendered":"[vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” top_padding=”2%” constrain_group_4=”yes” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” 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alignment_tablet=”default” alignment_phone=”default” display=”inline” display_tablet=”inherit” display_phone=”inherit” icon_family=”none” link_text=”Back to news” url=”\/mycotoxins-vn\/#news” text=”\u2190” font_size_desktop=”14px”][\/vc_column][\/vc_row][vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” constrain_group_4=”yes” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” top_padding=”2%” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”horizontal” column_element_direction_tablet=”horizontal” column_element_direction_phone=”horizontal” column_element_alignment=”center” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” font_color=”#269756″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][nectar_icon icon_family=”fontawesome” icon_style=”default” icon_color_type=”color_scheme” icon_color=”Extra-Color-1″ icon_padding=”0px” pointer_events=”all” icon_fontawesome=”fa fa-clock-o” icon_size=”15″ margin_right=”7px” margin_top=”1px”][vc_column_text][rt_reading_time label=”Reading Time:” postfix=”minutes” postfix_singular=”minute”][\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” top_padding=”2%” constrain_group_1=”yes” bottom_padding=”2%” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”padding-2-percent” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”left” left_margin=”7px” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”advanced” border_left_desktop=”1″ column_border_color=”#269756″ column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][vc_column_text el_class=”med”]\u0110\u1ed9c t\u00ednh c\u1ee7a fumonisin (FUM) c\u00f3 li\u00ean quan \u0111\u1ebfn vi\u1ec7c ng\u0103n ch\u1eb7n t\u1ed5ng h\u1ee3p ceramide (CerS), \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn tr\u1ea1ng th\u00e1i c\u00e2n b\u1eb1ng c\u1ee7a sphingolipids nh\u01b0 sphinganine (Sa) v\u00e0 sphingosine (So) trong t\u1ebf b\u00e0o<\/b>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” top_padding=”2%” constrain_group_1=”yes” bottom_padding=”2%” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text]Trong khi Sa t\u00edch l\u0169y trong t\u1ebf b\u00e0o, m\u1ee9c \u0111\u1ed9 So \u0111\u01b0\u1ee3c b\u00f9 \u0111\u1eafp, do \u0111\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn t\u1ef7 l\u1ec7 Sa: So \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng l\u00e0m d\u1ea5u \u1ea5n sinh h\u1ecdc khi ph\u01a1i nhi\u1ec5m v\u1edbi fumonisin \u1edf nhi\u1ec1u lo\u00e0i v\u1eadt nu\u00f4i. Tuy nhi\u00ean, <\/span>c\u00e1c c\u01a1 ch\u1ebf b\u00f9 tr\u1eeb \u0111\u1ec3 duy tr\u00ec m\u1ee9c ceramide trong t\u1ebf b\u00e0o<\/b> l\u00e0m cho vi\u1ec7c s\u1eed d\u1ee5ng d\u1ea5u \u1ea5n sinh h\u1ecdc n\u00e0y kh\u00f4ng c\u00f2n ph\u00f9 h\u1ee3p trong m\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u (t\u00f9y thu\u1ed9c v\u00e0o m\u1ee9c \u0111\u1ed9 v\u00e0 th\u1eddi gian ph\u01a1i nhi\u1ec5m). Th\u1eadt v\u1eady, trong nghi\u00ean c\u1ee9u n\u00e0y, <\/span>t\u1ef7 l\u1ec7 Sa: So kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a g\u00e0 ti\u1ebfp x\u00fac v\u1edbi fumonisin<\/b>. <\/span><\/p>\n

Tuy nhi\u00ean, m\u1ed9t ph\u00e2n t\u00edch \u0111\u1ea7y \u0111\u1ee7 <\/span>v\u1ec1 c\u00e1c lo\u1ea1i sphingolipid kh\u00e1c nhau<\/b> cho\u00a0 th\u1ea5y t\u1ef7 l\u1ec7 c\u00e1c d\u1ea1ng ph\u1ed1t ph\u00e1t c\u1ee7a Sa v\u00e0 So (Sa1P: So1P) \u0111\u00e3 t\u0103ng \u0111\u00e1ng k\u1ec3 b\u1eb1ng c\u00e1ch cho \u0103n th\u1ee9c \u0103n nhi\u1ec5m fumonisin. K\u1ebft qu\u1ea3 n\u00e0y ph\u00f9 h\u1ee3p v\u1edbi c\u00e1c k\u1ebft qu\u1ea3 tr\u01b0\u1edbc \u0111\u00f3 cho th\u1ea5y t\u1ef7 l\u1ec7 Sa1P: So1P l\u00e0 d\u1ea5u \u1ea5n sinh h\u1ecdc t\u1ed1t h\u01a1n cho vi\u1ec7c ph\u01a1i nhi\u1ec5m v\u1edbi fumonisins trong huy\u1ebft t\u01b0\u01a1ng so v\u1edbi t\u1ef7 l\u1ec7 Sa: So. T\u00e1c d\u1ee5ng t\u01b0\u01a1ng t\u1ef1 c\u1ee7a fumonisin \u0111\u00e3 \u0111\u01b0\u1ee3c quan s\u00e1t th\u1ea5y t\u00f9y theo k\u00edch th\u01b0\u1edbc c\u1ee7a chu\u1ed7i carbon c\u1ee7a ceramides.<\/span><\/p>\n

M\u1ed9t s\u1ef1 gia t\u0103ng \u0111\u00e1ng k\u1ec3 t\u1ef7 l\u1ec7 C22-C24: C16 \u0111\u00e3 \u0111\u01b0\u1ee3c quan s\u00e1t th\u1ea5y trong huy\u1ebft t\u01b0\u01a1ng. M\u1eb7c d\u00f9 c\u00e1c c\u01a1 ch\u1ebf \u0111\u1eb1ng sau nh\u1eefng t\u00e1c \u0111\u1ed9ng n\u00e0y v\u1eabn ch\u01b0a \u0111\u01b0\u1ee3c hi\u1ec3u r\u00f5, nh\u01b0ng k\u1ebft qu\u1ea3 n\u00e0y cho th\u1ea5y<\/span> t\u1ef7 l\u1ec7 sphingolipids C22-C24: C16, k\u1ebft h\u1ee3p v\u1edbi t\u1ef7 l\u1ec7 Sa1P: So1P, c\u00f3 th\u1ec3 l\u00e0 \u1ee9ng c\u1eed vi\u00ean t\u1ed1t \u0111\u1ec3 ph\u00e1t hi\u1ec7n s\u1ef1 ph\u01a1i nhi\u1ec5m fumonisin trong huy\u1ebft t\u01b0\u01a1ng g\u00e0 \u1edf li\u1ec1u kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn t\u1ef7 l\u1ec7 Sa: So<\/b>.<\/span>[\/vc_column_text][image_with_animation image_url=”16632″ image_size=”full” animation_type=”entrance” animation=”None” animation_movement_type=”transform_y” hover_animation=”none” alignment=”” border_radius=”none” box_shadow=”none” image_loading=”default” max_width=”100%” max_width_mobile=”default”][vc_column_text]H\u00ecnh: Ph\u00e2n t\u00edch ph\u00e2n bi\u1ec7t \u0111\u1ed1i x\u1eed (PLS-DA) c\u1ee7a sphingolipids trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a g\u00e0 \u0111\u01b0\u1ee3c cho \u0103n ch\u1ebf \u0111\u1ed9 \u0103n ki\u1ec3m so\u00e1t kh\u00f4ng c\u00f3 \u0111\u1ed9c t\u1ed1 n\u1ea5m m\u1ed1c v\u00e0 g\u00e0 \u0111\u01b0\u1ee3c cho \u0103n ch\u1ebf \u0111\u1ed9 \u0103n c\u00f3 ch\u1ee9a kho\u1ea3ng 15 mg FUM \/ kg trong 14 ho\u1eb7c 21 ng\u00e0y.<\/span><\/i>[\/vc_column_text][vc_column_text]Tham kh\u1ea3o: Lassallette E., Nyvall-Collen P., Guerre P., Sphingolipidomics nh\u1eafm m\u1ee5c ti\u00eau cho th\u1ea5y t\u1ef7 l\u1ec7 C22-C24: 16 t\u0103ng l\u00ean \u1edf h\u1ea7u h\u1ebft t\u1ea5t c\u1ea3 c\u00e1c l\u1edbp \u0111\u01b0\u1ee3c kh\u1ea3o nghi\u1ec7m \u1edf gan, th\u1eadn v\u00e0 huy\u1ebft t\u01b0\u01a1ng c\u1ee7a g\u00e0 \u0103n th\u1ee9c \u0103n nhi\u1ec5m fumonisin. \u0110\u1ed9c t\u00ednh sinh th\u00e1i v\u00e0 an to\u00e0n m\u00f4i tr\u01b0\u1eddng 268 (2023) 115697. <\/span><\/i>https:\/\/doi.org\/10.1016\/j.ecoenv.2023.115697<\/span><\/i><\/a>\u00a0<\/span><\/i>[\/vc_column_text][divider line_type=”Full Width Line” line_thickness=”1″ divider_color=”accent-color” custom_height=”20″][vc_column_text]Quan t\u00e2m \u0111\u1ebfn c\u00e1c nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1edfi nh\u00f3m nghi\u00ean c\u1ee9u n\u00e0y v\u1ec1 \u1ea3nh h\u01b0\u1edfng c\u1ee7a fumonisin l\u00ean g\u00e0?<\/b> \u0110\u1ecdc th\u00eam v\u1ec1 nghi\u00ean c\u1ee9u tr\u01b0\u1edbc \u0111\u00e2y c\u1ee7a h\u1ecd v\u1ec1 s\u1ef1 <\/a><\/span>t\u00edch t\u1ee5 FUM tr\u00ean gan v\u00e0 m\u00f4 v\u00fa \u1edf g\u00e0<\/a>, v\u00e0 l\u00e0m th\u1ebf n\u00e0o c\u00f4ng ngh\u1ec7 Olmix Algoclay c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m c\u00e1c t\u00e1c h\u1ea1i \u0111\u00f3<\/b>.<\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"

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